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Novel deep learning-based transcriptome data analysis
Real-time serum tissue

Novel deep learning-based transcriptome data analysis

Novel deep learning-based transcriptome information evaluation for drug-drug interplay prediction with an utility in diabetes

Background: Drug-drug interplay (DDI) is a critical public well being challenge. The L1000 database of the LINCS undertaking has collected hundreds of thousands of genome-wide expressions induced by 20,000 small molecular compounds on 72 cell traces. Whether or not this unified and complete transcriptome information useful resource can be utilized to construct a greater DDI prediction mannequin continues to be unclear. Due to this fact, we developed and validated a novel deep studying mannequin for predicting DDI utilizing 89,970 recognized DDIs extracted from the DrugBank database (model 5.1.4).
Outcomes: The proposed mannequin consists of a graph convolutional autoencoder community (GCAN) for embedding drug-induced transcriptome information from the L1000 database of the LINCS undertaking; and an extended short-term reminiscence (LSTM) for DDI prediction. Comparative analysis of varied machine studying strategies demonstrated the superior efficiency of our proposed mannequin for DDI prediction. Lots of our predicted DDIs have been revealed within the newest DrugBank database (model 5.1.7). Within the case research, we predicted medication interacting with sulfonylureas to trigger hypoglycemia and medicines interacting with metformin to trigger lactic acidosis, and confirmed each to induce results on the proteins concerned within the metabolic mechanism in vivo.
Conclusions: The proposed deep studying mannequin can speed up the invention of recent DDIs. It could actually help future medical analysis for safer and simpler drug co-prescription.
phrconference
phrconference

Genorise® Semen DNA Extraction Kit 500
GR101041 500
EUR 480

Genorise® Semen DNA Extraction Kit 200
GR101042 200
EUR 258

Genorise® Semen DNA Extraction Kit 100
GR101043 100
EUR 144

Genorise® Semen DNA Extraction Kit 50
GR101044 50
EUR 87

Genorise® Semen Stain DNA Extraction Kit 1000
GR101017 1000
EUR 1045

Genorise® Semen Stain DNA Extraction Kit 500
GR101069 500
EUR 564

Genorise® Semen Stain DNA Extraction Kit 200
GR101070 200
EUR 243

Genorise® Semen Stain DNA Extraction Kit 100
GR101071 100
EUR 144

Genorise® Semen Stain DNA Extraction Kit 50
GR101072 50
EUR 87

AI-91K LN2 Freezer for Bulk Semen Storage, no controller
TW-AI-91K 1 UNIT
EUR 66671
Description: AI-91K LN2 Freezer for Bulk Semen Storage, no controller

Semenogelin I Protein
20-abx261182
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Semenogelin I antibody
70R-1587 100 ug
EUR 452.4
Description: Rabbit polyclonal Semenogelin I antibody raised against the N terminal of SEMG1

Semenogelin I antibody
70R-1593 100 ug
EUR 452.4
Description: Rabbit polyclonal Semenogelin I antibody raised against the C terminal of SEMG1

Semenogelin I antibody
70R-5491 50 ug
EUR 560.4
Description: Rabbit polyclonal Semenogelin I antibody raised against the middle region of SEMG1

Semenogelin I (SEMG1) Antibody
abx237711-100ug 100 ug
EUR 661.2

Semenogelin I (SEMG1) Antibody
20-abx174508
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Semenogelin I (SEMG1) Antibody
20-abx322135
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Semenogelin I (SEMG1) Antibody
20-abx115422
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Semenogelin I (SEMG1) Antibody
abx028130-400ul 400 ul
EUR 627.6

Semenogelin I (SEMG1) Antibody
abx028130-80l 80 µl
EUR 343.2

Semenogelin I (SEMG1) Antibody
20-abx129235
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Semenogelin I (SEMG1) Antibody
20-abx320262
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Semenogelin I (SEMG1) Antibody
20-abx004204
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Recombinant Semenogelin I (SEMG1)
4-RPH185Hu01
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Semenogelin I expressed in: E.coli

Semenogelin I Blocking Peptide
33R-7601 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of SEMG1 antibody, catalog no. 70R-1587

Semenogelin I Blocking Peptide
33R-3239 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of SEMG1 antibody, catalog no. 70R-1593

Semenogelin I Blocking Peptide
33R-4289 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of SEMG1 antibody, catalog no. 70R-5491

Human Semenogelin I (SEMG1) Protein
20-abx168081
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Semenogelin I (SEMG1) CLIA Kit
20-abx495402
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Lung Diabetic Disease Lysate
XBL-10362 0.1 mg
EUR 796.2
Description: Human lung tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human lung tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the lung tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The lung tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Human Semenogelin I (SEMG1) ELISA Kit
abx250766-96tests 96 tests
EUR 904.8

Human Semenogelin I (SEMG1) ELISA Kit
abx571776-96tests 96 tests
EUR 904.8

Human Semenogelin I (SEMG1) ELISA Kit
DLR-SEMG1-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Semenogelin I (SEMG1) in samples from serum, plasma, seminal plasma or other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
DLR-SEMG1-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Semenogelin I (SEMG1) in samples from serum, plasma, seminal plasma or other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
20-abx153055
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Semenogelin I (SEMG1) ELISA Kit
RDR-SEMG1-Hu-48Tests 48 Tests
EUR 652.8

Human Semenogelin I (SEMG1) ELISA Kit
RDR-SEMG1-Hu-96Tests 96 Tests
EUR 907.2

Human Semenogelin I (SEMG1) ELISA Kit
RD-SEMG1-Hu-48Tests 48 Tests
EUR 625.2

Human Semenogelin I (SEMG1) ELISA Kit
RD-SEMG1-Hu-96Tests 96 Tests
EUR 867.6

Human Semenogelin I(SEMG1)ELISA Kit
QY-E01566 96T
EUR 448.8

Human Semenogelin I (SEMG1) ELISA Kit
SEH185Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Semenogelin I (SEMG1) in serum, plasma, seminal plasma and other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
SEH185Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Semenogelin I (SEMG1) in serum, plasma, seminal plasma and other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
SEH185Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Semenogelin I (SEMG1) in serum, plasma, seminal plasma and other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
SEH185Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Semenogelin I (SEMG1) in serum, plasma, seminal plasma and other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
4-SEH185Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Semenogelin I (SEMG1) in samples from serum, plasma, seminal plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Semenogelin I (SEMG1) ELISA Kit
RDR-SEMG1-Hu-48T 48T
EUR 475.34
Description: serum, plasma, seminal plasma and other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
RDR-SEMG1-Hu-96T 96T
EUR 679.04
Description: serum, plasma, seminal plasma and other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
RD-SEMG1-Hu-48T 48T
EUR 452.7
Description: serum, plasma, seminal plasma and other biological fluids.

Human Semenogelin I (SEMG1) ELISA Kit
RD-SEMG1-Hu-96T 96T
EUR 646.7
Description: serum, plasma, seminal plasma and other biological fluids.

Total RNA - Diabetic Disease: Colon
R1236090Dia-50 50 ug
EUR 421.2

Colon Diabetic Disease Lysate
XBL-10333 0.1 mg
EUR 796.2
Description: Human colon tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human colon tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the colon tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The colon tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Ileum Diabetic Disease Lysate
XBL-10379 0.1 mg
EUR 796.2
Description: Human small intestine: Ileum tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human small intestine: Ileum tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the small intestine: Ileum tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The small intestine: Ileum tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Total RNA - Diabetic Disease: Stomach
R1236248Dia-50 50 ug
EUR 421.2

Jejunum Diabetic Disease Lysate
XBL-10381 0.1 mg
EUR 796.2
Description: Human small intestine: Jejunum tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human small intestine: Jejunum tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the small intestine: Jejunum tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The small intestine: Jejunum tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Stomach Diabetic Disease Lysate
XBL-10387 0.1 mg
EUR 796.2
Description: Human stomach tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human stomach tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the stomach tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The stomach tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Total RNA - Diabetic Disease: Pancreas
R1236188Dia-50 50 ug
EUR 421.2

Duodenum Diabetic Disease Lysate
XBL-10336 0.1 mg
EUR 796.2
Description: Human duodenum tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human duodenum tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the duodenum tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The duodenum tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

ELISA kit for Human SEMG1 (Semenogelin I)
ELK4641 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Semenogelin I from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Total RNA - Diabetic Disease: Esophagus
R1236106Dia-50 50 ug
EUR 421.2

Esophagus Diabetic Disease Lysate
XBL-10338 0.1 mg
EUR 796.2
Description: Human esophagus tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human esophagus tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the esophagus tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The esophagus tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Pancrease Diabetic Disease Lysate
XBL-10371 0.1 mg
EUR 796.2
Description: Human pancrease tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human pancrease tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the pancrease tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The pancrease tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

cDNA - Human Diabetic Diseased Tissue: Lung
C1236152Dia 40 reactions
EUR 729

cDNA - Human Diabetic Diseased Tissue: Skin
C1236218Dia 40 reactions
EUR 729

cDNA - Human Diabetic Diseased Tissue: Brain
C1236035Dia 40 reactions
EUR 729

cDNA - Human Diabetic Diseased Tissue: Colon
C1236090Dia 40 reactions
EUR 729

cDNA - Human Diabetic Diseased Tissue: Heart
C1236122Dia 40 reactions
EUR 729

cDNA - Human Diabetic Diseased Tissue: Liver
C1236149Dia 40 reactions
EUR 729

SEMG1 Semenogelin I Human Recombinant Protein
PROTP04279 Regular: 20ug
EUR 380.4
Description: SEMG1 Human Recombinant produced in E. coli is a single polypeptide chain containing 462 amino acids (24-462) and having a molecular mass of 52kDa. SEMG1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Semenogelin I (SEMG1) Polyclonal Antibody (Human)
4-PAH185Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Semenogelin I (SEMG1)

cDNA - Human Diabetic Diseased Tissue: Whole Eye
C1236108Dia-10 10 reactions
EUR 393

cDNA - Human Diabetic Diseased Tissue: Kidney
C1236142Dia 40 reactions
EUR 729

cDNA - Human Diabetic Diseased Tissue: Spleen
C1236246Dia 40 reactions
EUR 729

Skeletal Muscle Diabetic Disease Lysate
XBL-10369 0.1 mg
EUR 796.2
Description: human skeletal muscle tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human skeletal muscle tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the Skeletal Muscle tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The Skeletal Muscle tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Collagen Type I (Collagen Type I) Antibody
abx231836-100ug 100 ug
EUR 610.8

Collagen Type I (Collagen Type I) Antibody
abx020882-100ug 100 ug
EUR 1161.6

Collagen Type I (Collagen Type I) Antibody
abx022733-05ml 0.5 ml
EUR 1713.6

Collagen Type I (Collagen Type I) Antibody
abx022734-02mg 0.2 mg
EUR 1312.8

Collagen Type I (Collagen Type I) Antibody
abx022736-05ml 0.5 ml
EUR 1696.8

Collagen Type I (Collagen Type I) Antibody
abx022737-05ml 0.5 ml
EUR 1412.4

Collagen Type I (Collagen Type I) Antibody
20-abx101265
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Collagen Type I (Collagen Type I) Antibody
20-abx101266
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Collagen Type I (Collagen Type I) Antibody
20-abx130515
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

cDNA - Human Diabetic Diseased Tissue: Lymph Node
C1236161Dia-10 10 reactions
EUR 393

cDNA - Human Diabetic Diseased Tissue: Stomach
C1236248Dia 40 reactions
EUR 729

cDNA - Human Diabetic Diseased Tissue: Bone Marrow
C1236024Dia-10 10 reactions
EUR 420

cDNA - Human Diabetic Diseased Tissue: Pancreas
C1236188Dia 40 reactions
EUR 729

Pancreas Membrane Diabetic Disease Lysate
XBL-10785 0.1 mg
EUR 752.1
Description: Human pancreas tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human pancreas tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated pancreas tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated pancreas tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

cDNA - Human Diabetic Diseased Tissue: Esophagus
C1236106Dia 40 reactions
EUR 729

Membrane Protein - Diabetic Disease: Pancreas
P3236188Dia 0.1 mg
EUR 410

Semenogelin I (SEMG1) Polyclonal Antibody (Human), PE
4-PAH185Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Semenogelin I (SEMG1). This antibody is labeled with PE.

Semenogelin I (SEMG1) Polyclonal Antibody (Human), APC
4-PAH185Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Semenogelin I (SEMG1). This antibody is labeled with APC.

Semenogelin I (SEMG1) Polyclonal Antibody (Human), Cy3
4-PAH185Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Semenogelin I (SEMG1). This antibody is labeled with Cy3.

Semenogelin I (SEMG1) Polyclonal Antibody (Human), HRP
4-PAH185Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Semenogelin I (SEMG1). This antibody is labeled with HRP.

Total Protein - Human Diabetic Diseased Tissue: Lung
P1236152Dia 1 mg
EUR 471

Total Protein - Human Diabetic Diseased Tissue: Skin
P1236218Dia 1 mg
EUR 471

Semenogelin I (SEMG1) Polyclonal Antibody (Human), FITC
4-PAH185Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Semenogelin I (SEMG1). This antibody is labeled with FITC.

Adipose Subcutaneous Diabetic Disease Lysate
20-105 0.1 mg
EUR 1508.1
Description: Human subcutaneous adipose tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human subcutaneous adipose tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the subcutaneous adipose tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The subcutaneous adipose tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Total Protein - Human Diabetic Diseased Tissue: Brain
P1236035Dia 1 mg
EUR 471

Total Protein - Human Diabetic Diseased Tissue: Colon
P1236090Dia 1 mg
EUR 471

Total Protein - Human Diabetic Diseased Tissue: Heart
P1236122Dia 1 mg
EUR 471

Total Protein - Human Diabetic Diseased Tissue: Liver
P1236149Dia 1 mg
EUR 471

cDNA - Human Diabetic Diseased Tissue: Skeletal Muscle
C1236171Dia 40 reactions
EUR 729

Total Protein - Human Diabetic Diseased Tissue: Whole Eye
P1236108Dia 1 mg
EUR 1147

Total Protein - Human Diabetic Diseased Tissue: Kidney
P1236142Dia 1 mg
EUR 471

Total Protein - Human Diabetic Diseased Tissue: Spleen
P1236246Dia 1 mg
EUR 471

Skeletal Muscle Membrane Diabetic Disease Lysate
XBL-10855 0.1 mg
EUR 752.1
Description: human skeletal muscle tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human skeletal muscle tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated Skeletal Muscle tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated Skeletal Muscle tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

cDNA - Human Diabetic Diseased Tissue: Visceral Adipose
C1236003VisDia-10 10 reactions
EUR 420

Membrane Protein - Diabetic Disease: Skeletal Muscle
P3236171Dia 0.1 mg
EUR 410

Total Protein - Human Diabetic Diseased Tissue: Adrenal
P1236004Dia 1 mg
EUR 471

Total Protein - Human Diabetic Diseased Tissue: Stomach
P1236248Dia 1 mg
EUR 471

Total Protein - Human Diabetic Diseased Tissue: Bone Marrow
P1236024Dia 1 mg
EUR 1147

Total Protein - Human Diabetic Diseased Tissue: Pancreas
P1236188Dia 1 mg
EUR 471

Frozen Tissue Section - Human Diabetic Diseased Tissue: Eye
T1236108Dia 5 slides
EUR 662

cDNA - Human Diabetic Diseased Tissue: Small Intestine: Ileum
C1236227Dia 40 reactions
EUR 729

Total Protein - Human Diabetic Diseased Tissue: Esophagus
P1236106Dia 1 mg
EUR 471

Frozen Tissue Section - Human Diabetic Diseased Tissue: Lung
T1236152Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Skin
T1236218Dia 5 slides
EUR 475

Semenogelin I (SEMG1) Polyclonal Antibody (Human), APC-Cy7
4-PAH185Hu01-APC-Cy7
  • EUR 685.20
  • EUR 7716.00
  • EUR 2046.00
  • EUR 912.00
  • EUR 382.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Semenogelin I (SEMG1). This antibody is labeled with APC-Cy7.

Frozen Tissue Section - Human Diabetic Diseased Tissue: Brain
T1236035Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Colon
T1236090Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Heart
T1236122Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Liver
T1236149Dia 5 slides
EUR 475

Semenogelin I (SEMG1) Polyclonal Antibody (Human), Biotinylated
4-PAH185Hu01-Biotin
  • EUR 373.20
  • EUR 2952.00
  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Semenogelin I (SEMG1). This antibody is labeled with Biotin.

cDNA - Human Diabetic Diseased Tissue: Subcutaneous Adipose
C1236003SubDia-10 10 reactions
EUR 420

cDNA - Human Diabetic Diseased Tissue: Small Intestine: Jejunum
C1236230Dia 40 reactions
EUR 729

Genomic DNA - Human Diabetic Diseased Tissue: Lung, from a single donor
D1236152Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Skin, from a single donor
D1236218Dia 50 ug
EUR 489

Frozen Tissue Section - Human Diabetic Diseased Tissue: Kidney
T1236142Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Spleen
T1236246Dia 5 slides
EUR 475

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Lung
T2236152Dia 5 slides
EUR 238

cDNA - Human Diabetic Diseased Tissue: Small Intestine: Duodenum
C1236101Dia 40 reactions
EUR 729

Genomic DNA - Human Diabetic Diseased Tissue: Colon, from a single donor
D1236090Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Heart, from a single donor
D1236122Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Liver, from a single donor
D1236149Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Brain, from a single donor
D1236035Dia 50 ug
EUR 489

Total Protein - Human Diabetic Diseased Tissue: Skeletal Muscle
P1236171Dia 1 mg
EUR 471

Frozen Tissue Section - Human Diabetic Diseased Tissue: Adrenal
T1236004Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Stomach
T1236248Dia 5 slides
EUR 475

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Colon
T2236090Dia 5 slides
EUR 238

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Liver
T2236149Dia 5 slides
EUR 238

Genomic DNA - Human Diabetic Diseased Tissue: Whole Eye, from a single donor
D1236108Dia 50 ug
EUR 1152

Genomic DNA - Human Diabetic Diseased Tissue: Kidney, from a single donor
D1236142Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Spleen, from a single donor
D1236246Dia 50 ug
EUR 489

Total Protein - Human Diabetic Diseased Tissue: Visceral Adipose
P1236003VisDia 1 mg
EUR 1147

Frozen Tissue Section - Human Diabetic Diseased Tissue: Bone Marrow
T1236024Dia 5 slides
EUR 662

Frozen Tissue Section - Human Diabetic Diseased Tissue: Pancreas
T1236188Dia 5 slides
EUR 475

Genomic DNA - Human Diabetic Diseased Tissue: Stomach, from a single donor
D1236248Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Adrenal, from a single donor
D1236004Dia 50 ug
EUR 489

Frozen Tissue Section - Human Diabetic Diseased Tissue: Esophagus
T1236106Dia 5 slides
EUR 475

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Stomach
T2236248Dia 5 slides
EUR 238

Genomic DNA - Human Diabetic Diseased Tissue: Esophagus, from a single donor
D1236106Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Pancreas, from a single donor
D1236188Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Bone Marrow, from a single donor
D1236024Dia 50 ug
EUR 1152

Total Protein - Human Diabetic Diseased Tissue: Small Intestine: Ileum
P1236227Dia 1 mg
EUR 471

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Bone Marrow
T2236024Dia 5 slides
EUR 238

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Esophagus
T2236106Dia 5 slides
EUR 238

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Pancreas
T2236188Dia 5 slides
EUR 238

Total Protein - Human Diabetic Diseased Tissue: Subcutaneous Adipose
P1236003SubDia 1 mg
EUR 1147

Total Protein - Human Diabetic Diseased Tissue: Small Intestine: Duodenum
P1236101Dia 1 mg
EUR 471

Total Protein - Human Diabetic Diseased Tissue: Small Intestine: Jejunum
P1236230Dia 1 mg
EUR 471

Frozen Tissue Section - Human Diabetic Diseased Tissue: Visceral Adipose
T1236003VisDia 5 slides
EUR 662

Frozen Tissue Section - Human Diabetic Diseased Tissue: Skeletal Muscle
T1236171Dia 5 slides
EUR 475

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Parathyroid
T2236189Dia 5 slides
EUR 629

Genomic DNA - Human Diabetic Diseased Tissue: Skeletal Muscle, from a single donor
D1236171Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Visceral Adipose, from a single donor
D1236003VisDia 50 ug
EUR 1152

Frozen Tissue Section - Human Diabetic Diseased Tissue: Small Intestine: Ileum
T1236227Dia 5 slides
EUR 475

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Skeletal Muscle
T2236171Dia 5 slides
EUR 238

Genomic DNA - Human Diabetic Diseased Tissue: Small Intestine: Ileum, from a single donor
D1236227Dia 50 ug
EUR 489

Frozen Tissue Section - Human Diabetic Diseased Tissue: Subcutaneous Adipose
T1236003SubDia 5 slides
EUR 662

Frozen Tissue Section - Human Diabetic Diseased Tissue: Small Intestine: Jejunum
T1236230Dia 5 slides
EUR 475

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Small Intestine: Ileum
T2236227Dia 5 slides
EUR 238

Genomic DNA - Human Diabetic Diseased Tissue: Small Intestine: Jejunum, from a single donor
D1236230Dia 50 ug
EUR 489

Genomic DNA - Human Diabetic Diseased Tissue: Subcutaneous Adipose, from a single donor
D1236003SubDia 50 ug
EUR 1152

Frozen Tissue Section - Human Diabetic Diseased Tissue: Small Intestine: Duodenum
T1236101Dia 5 slides
EUR 475

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Small Intestine: Jejunum
T2236230Dia 5 slides
EUR 238

Procollagen Type I (212-216)
H-1592.0005 5.0mg
EUR 151.2
Description: Sum Formula: C23H45N7O9; CAS# [149128-48-3]

Procollagen Type I (212-216)
H-1592.0025 25.0mg
EUR 501.6
Description: Sum Formula: C23H45N7O9; CAS# [149128-48-3]

Collagen Type I protein
30R-AC016 500 ug
EUR 528
Description: Purified native Human Collagen Type I Solution

Collagen Type I protein
E62L001 1mg
EUR 1425.6

Genomic DNA - Human Diabetic Diseased Tissue: Small Intestine: Duodenum, from a single donor
D1236101Dia 50 ug
EUR 489

Paraffin Tissue Section - Human Diabetic Diseased Tissue: Small Intestine: Duodenum
T2236101Dia 5 slides
EUR 238

Collagen Type I antibody
10-1800 200 ul
EUR 846
Description: Mouse monoclonal Collagen Type I antibody

Collagen Type I antibody
10R-C139b 100 ug
EUR 976.8
Description: Mouse monoclonal Collagen Type I antibody

Collagen Type I antibody
20R-CR025 500 ul
EUR 950.4
Description: Rabbit polyclonal Collagen Type I antibody

Collagen Type I antibody
70R-CR007x 100 µg
EUR 379.2
Description: Affinity purified Rabbit polyclonal Collagen Type I antibody

Collagen Type I antibody
PAab09910 100 ug
EUR 463.2

Procollagen Type I protein
E62L008 100ug
EUR 1035.6

Type I Safety Can 4L
SAF7976 EACH
EUR 143.62

The Welsh Consuming Dysfunction Service Evaluate 2018, Scottish Consuming Dysfunction Service Evaluate 2021 and proposals of greatest apply in comorbid consuming problems and diabetes

Background: Diabetes and consuming problems are steadily comorbid. This explicit comorbidity just isn’t solely usually poorly recognised, however is tough to deal with and has a excessive mortality.
Methodology: On this article, we’ll briefly evaluation the connection between diabetes and consuming problems. We are going to evaluation the present NICE and different steering and studies regarding each diabetes and consuming problems in the UK. We are going to then describe the suggestions of the 2018 Welsh Authorities Consuming Dysfunction Service Evaluate and the 2021 the Scottish Authorities Consuming Dysfunction Service Evaluate concerning diabetes and consuming problems, which is able to result in service change.
Conclusions: We conclude that this can be a comparatively underdeveloped however necessary space the place there must be additional service improvement and extra collaboration between diabetes and consuming dysfunction providers.

Security of Dapagliflozin in Sufferers with Kind 2 Diabetes Mellitus in Saudi Arabia: A Put up Authorization Security Research

Introduction: Sodium-glucose co-transporter-2 (SGLT2) inhibitors reasonably scale back glucose ranges in type-2 diabetes mellitus (T2DM). Some instances of diabetic ketoacidosis (DKA) have been reported with SGLT2 inhibitors. Nevertheless, information on the long-term security of dapagliflozin in Saudi Arabia are missing. The current research aimed to watch the protection of dapagliflozin in sufferers with T2DM and consider the change in HbA1c through the remark interval in comparison with baseline.
Strategies: This was an area, potential, single-arm, non-interventional, regulatory post-marketing research. The research was performed in Saudi Arabia from Might 2017 to September 2019. Sufferers acquired both 5 or 10 mg dapagliflozin together with weight loss program and train modifications to deal with T2DM. The incidence of antagonistic occasions was noticed over the therapy period and for Three days after administering the final dose of dapagliflozin.
Outcomes: A complete of 527 sufferers have been recruited within the research, 524 of which have been eligible for the statistical evaluation. About 62% have been males. The median (IQR) age was 52.3 (14.8) years, whereas the median (IQR) physique mass index was 31.6 (7.7) kg/m2. The median (IQR) period because the sufferers have been first identified with T2DM was 8.78 (6.73) years. The commonest comorbidities have been hyperlipidemia (51.1%) and hypertension (41.1%). Virtually three-quarters of the research inhabitants (73.7%) acquired different antidiabetic drugs along with dapagliflozin.
Over a interval of 12 months, a complete of 106 antagonistic occasions have been skilled by 65 (12.33%) sufferers. Vulvovaginal pruritus (3.1%), dysuria (2.7%), polyuria (1.3%), urinary tract infections (1%), fatigue (0.8%), and hypoglycemia (0.8%) have been among the many reported antagonistic occasions. One case of DKA (0.2%) was reported. The imply (SD) HbA1c% degree considerably decreased from 8.6 (1.6) % at baseline to succeed in 7.2 (1.2) % after 12 months of therapy (p < 0.0001).
Conclusion: Dapagliflozin was discovered to be a effectively tolerated and efficient therapy possibility for T2DM sufferers in Saudi Arabia. Vulvovaginal pruritus and dysuria have been the commonest antagonistic occasions.

Espresso consumption and cardiovascular illnesses and mortality in sufferers with kind 2 diabetes: A scientific evaluation and dose-response meta-analysis of cohort research

Goals: To judge the long-term penalties of espresso ingesting in sufferers with kind 2 diabetes.
Information synthesis: PubMed, Scopus, and Net of Sciences have been searched to November 2020 for potential cohort research evaluating the affiliation of espresso ingesting with danger of heart problems (CVD) and mortality in sufferers with kind 2 diabetes. Two reviewers extracted information and rated the certainty of proof utilizing GRADE method. Random-effects fashions have been used to estimate the hazard ratios (HRs) and 95% CIs. Dose-response associations have been modeled by a one-stage mixed-effects meta-analysis. Ten potential cohort research with 82,270 instances have been included. In comparison with these with no espresso consumption,
the HRs for consumption of Four cups/d have been 0.79 (95%CI: 0.72, 0.87; n = 10 research) for all-cause mortality, 0.60 (95%CI: 0.46, 0.79; n = 4) for CVD mortality, 0.68 (95%CI: 0.51, 0.91; n = 3) for coronary coronary heart illness (CHD) mortality, 0.72 (95%CI: 0.54, 0.98; n = 2) for CHD, and 0.77 (95%CI: 0.61, 0.98; n = 2) for whole CVD occasions. There was no vital affiliation for most cancers mortality and stroke. There was an inverse monotonic affiliation between espresso ingesting and all-cause and CVD mortality, and inverse linear affiliation for CHD and whole CVD occasions. The understanding of proof was graded average for all-cause mortality, and low or very low for different outcomes.
Conclusions: Consuming espresso could also be inversely related to the danger of mortality in sufferers with kind 2 diabetes. Nevertheless, extra analysis is required contemplating kind of espresso, sugar and cream added to espresso, and historical past of CVD to current extra assured outcomes.
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